What is Cushing’s syndrome? The hormone disorder Amy Schumer was diagnosed with

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Amy Schumer has revealed she’s been diagnosed with Cushing’s syndrome after receiving quite a few feedback about her look throughout her Life & Beth press tour.

In the “News Not Noise” letter printed on 23 February, Jessica Yellin revealed that the famed comic had “exogenous Cushing syndrome, brought on by getting steroid injections in high doses”.

Cushing’s Syndrome is when the physique produces an excessive amount of of the hormone cortisol. “This can result from the body making too much cortisol, or from taking medicines called glucocorticoids, which affect the body the same way as cortisol,” in accordance with Mayo Clinic.

There are two forms of the disorder: exogenous and endogenous. Exogenous Cushing’s syndrome happens from elements outdoors the physique, whereas endogenous Cushing’s syndrome happens from elements contained in the physique. Per an Endocrine Society report, signs stemming from the disorder are the identical whatever the kind. However, endogenous is rarer and will be probably brought on by a tumour that’s producing an excessive amount of cortisol.

Symptoms can embody weight achieve within the bottom and face, stretch marks (particularly on the abdomen, hips, breasts, arms, and thighs), simply bruised pores and skin, pimples, sluggish pores and skin therapeutic, and a “fatty lump between the shoulders,” in accordance with the Mayo Clinic.

Hirsutism, the expansion of thick and darkish hair, is a standard symptom seen in girls who’re experiencing Cushing’s syndrome. Additionally, girls with the disorder can both cease getting their interval or their interval might turn into much less frequent.

Men with Cushing’s syndrome might expertise a decrease intercourse drive, points performing sexual exercise, and decreased fertility.

Other frequent signs for each women and men are elevated tiredness, muscle weak point, complications, infections, bone loss, hypertension, and pores and skin darkening.

Speaking to Yellin, Schumer detailed how she was feeling bodily. First, she famous how her prognosis happened.

“While I was doing press on camera for my Hulu show, I was also in MRI machines four hours at a time, having my veins shut down from the amount of blood drawn and thinking I may not be around to see my son grow up,” the 42-year-old actress stated.

“So finding out I have the kind of Cushing that will just work itself out and I’m healthy was the greatest news imaginable. It has been a crazy couple weeks for me and my family,” she continued.

Overall, Schumer stated she felt “reborn” after studying the prognosis, and that it is curable.

Cushing’s syndrome is utterly treatable and will be cured. Medicines embody “ketoconazole, osilodrostat (Isturisa), mitotane (Lysodren), levoketoconazole (Recorlev), and metyrapone (Metopirone),” per the Mayo Clinic.