Pioneer of America’s global HIV/AIDS program recalls hope after years of despair

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  • Dr. John Nkengasong, who at present oversees the global AIDS effort, recalls the determined scenes in Africa earlier than the introduction of PEPFAR in 2004.
  • PEPFAR, initiated by the Bush administration, has revolutionized HIV care, saving an estimated 25 million lives in hard-hit nations.
  • Funding debates in Congress threaten the program’s future, he mentioned.

Through his workplace window at what was then one of Africa’s few fashionable clinics coping with HIV and AIDS, the person who now oversees the United States’ threatened global AIDS effort used to listen to the sound of taxis pulling up all through the day.

If he turned his head to look out the window, Dr. John Nkengasong mentioned, he knew what he would see: one other determined household carrying a dying beloved one — a person or girl already lapsing right into a coma, a stick-thin little one — and hoping to search out assist.

It was earlier than the Bush administration began the U.S. President’s Emergency Relief Plan for AIDS Relief, referred to as PEPFAR, in 2004. There was nearly no inexpensive efficient remedy anyplace between South Africa and the Sahara, no fast HIV assessments or high-quality authorities labs, and few beds for AIDS sufferers.

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Nkengasong has spent many years working in Africa on HIV and AIDS, a profession intertwined with the U.S. program that since its introduction 20 years in the past has remodeled care in some of the hardest-hit nations and saved an estimated 25 million lives. He spoke to The Associated Press throughout a battle over funding in Congress that imperils the AIDS program’s future.

John Nkengasong

Ambassador-at-Large John Nkengasong, new head of the Bureau of Global Health Security and Diplomacy on the State Department, speaks throughout the 2023 Concordia Annual Summit on Sept. 19, 2023, in New York City. Nkengasong has spent many years working in Africa on HIV and AIDS. (Riccardo Savi/Getty Images for Concordia Summit)

Opponents say the HIV/AIDS funding might be not directly supporting abortion overseas, though the Biden administration and PEPFAR’s defenders say there isn’t any proof that it does. After a handful of conservative lawmakers threatened for months to dam the funding except restrictions had been hooked up, a compromise was struck in late March that extends the funding for a yr.

But advocates of the program warn that with out the total five-year renewal, its future stays doubtful because the political debate over abortion and reproductive rights solely turns into extra combative.

Before PEPFAR, generally, Nkengasong’s infectious illness clinic in Abidjan, within the Ivory Coast, might provide the households no care. In their family members’ final hours, the households who got here there usually had been left to crouch exterior, within the parking zone.

They would encompass “a skeleton of a human being, with a tinge of flesh over their bodies,” Nkengasong recalled. “They held their loved ones, giving them the best comfort they could.”

Soon sufficient, the sound of wailing would rise by way of his home windows. The cries signaled one other dying to HIV/AIDS, one of tens of millions in Africa by the mid-2000s.

The scene can be repeated “nearly hour by hour,” Nkengasong mentioned. Sometimes he would stand up and shut the curtains, blocking out the distress of an epidemic he couldn’t then stem.

Two many years later, Nkengasong says, his journeys to the area from his workplaces in Washington carry joyous conferences with males, girls and youngsters whose lives had been saved by way of PEPFAR, credited as the largest authorities effort ever in opposition to a single illness.

In all, the U.S. program has spent greater than $110 billion on HIV care and remedy, native medical methods and social packages aimed toward stemming an infection. The U.S. says it has saved 25 million lives in sub-Saharan Africa and different weak areas, together with these of 5.5 million kids.

‘A THRIVING INDUSTRY OF COFFINS’

Nkengasong, who was born in Cameroon and did his graduate research in Belgium, labored in Africa within the Nineties, when the AIDS epidemic was raging all however unchecked.

It made for a “thriving industry of coffins,” he mentioned. Visiting cities in Uganda, Rwanda, Kenya and elsewhere for his work on infectious illnesses, he would journey streets lined by handmade coffins of all sizes.

Beds of infectious-disease clinics had been full of “adults lying there looking like babies, because of what HIV had done. That ugly face,” Nkengasong recalled.

With early retroviral medicine averaging $10,000 per affected person per yr, solely 50,000 HIV-infected individuals in sub-Saharan Africa had been estimated to be receiving efficient remedy within the mid-to-late Nineties. That was out of what the World Health Organization mentioned was 10 million individuals there residing with HIV and AIDS.

THE ‘AHA’ MOMENT

One day in spring 2002, as he was in his lab conducting assessments, a big American delegation immediately arrived on the clinic in Abidjan.

Health Secretary Tommy Thompson and different main U.S. well being officers crowded into the ability, together with representatives of companies and members of faith-based organizations.

“I remember opening the door and the first person who walked through was Dr. Fauci,” Nkengasong recounted. Anthony Fauci, a number one HIV researcher, was then a prime official on the U.S. National Institutes of Health and a frontrunner in Nkengasong’s subject of HIV and AIDS work. “And he said, ‘John, good to see you again.’ And I was so excited.”

Unbeknownst to Nkengasong and his colleagues, nationwide safety adviser Condoleeza Rice and different officers privately had been making the case to President George W. Bush that the global HIV epidemic was the place the U.S. might make an enormous distinction.

For the Bush administration, the epidemic introduced a chance to do good at a time when the U.S. was waging struggle in Afghanistan and later Iraq as nicely after the Sept. 11, 2001 assaults.

Nine months after the Americans confirmed up in his lab, “we’re watching news on CNN, it was the State of the Union address,” Nkengason recalled. “And President Bush announced the start of PEPFAR.”

That night time, the president pledged an preliminary $15 billion over the subsequent 5 years to deal with the AIDS epidemic world wide.

Nkengason referred to as it the “aha moment” for himself and others combating AIDS in probably the most weak area of the world.

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Two many years later, AIDS deaths globally have fallen almost 70% from their peak in 2004. Sub-Saharan Africa continues to be probably the most weak area and residential to two-thirds of the individuals residing with HIV. But the PEPFAR program and others have strengthened well being care methods to cope with infectious illnesses, made remedy obtainable to tens of millions, and expanded assist for probably the most at-risk populations, together with girls.

On a visit again to Abidjan, Nkengasong met a wholesome 17-year-old lady, one of tens of millions spared from an infection at delivery because of medical remedy that prevented HIV transmission from their contaminated moms.

This previous summer time, he visited a clinic in Namibia the place HIV-infected moms had delivered “super healthy” infants because of remedy that saved them from an infection.

“I grabbed some of the babies and looked at them,” he mentioned. Holding them, he puzzled what would have occurred to them with out correct care.

“And they just give you that smile,” he mentioned.

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